Background and Purpose: Today, much attention has been considered in the prevention of cardiovascular diseases. In some parts of the world the rates of cardiovascular disease is low due to a Mediterranean diet containing olive oil. This systematic review studies the verses and traditions to express opinions on olive and comparison it with the findings of modern medicine.

Methods and Materials: This is a library research of studies from data collected in the Qur'an, traditions, and related articles on the Internet, limited to English and Persian, and without time limitation by using the keywords :olive (in Persian), olive, heart disease , Mediterranean diet, And viewpoints of Quran and Hadith about the cardiovascular effects of olive fruit consumption.

Results: Systematic review demonstrated that in the Quran olive is a clear sign to scientists. Its use is recommended in the authentic traditions. Also the results showed that consumption of olive is effective in reducing mortality and incidence of cardiovascular diseases.

Conclusion: Olive, a clear indication of God, is effective in preventing cardiovascular diseases. Experimental Investigation of the effect of the fruit in the prevention of cardiovascular diseases is recommended.