Revival of Traditional Iranian Medicine provides an opportunity for researchers to get benefits from the valuable therapeutic measures of past traditional physicians (The Hakims). In this way, researchers can achieve therapeutic methods with less complications and lower costs. Because of its high prevalence and direct relationship with cardiovascular disorders, hyperlipidemia is a major health concern. According to the Traditional Iranian Medicine texts, one of the basic issues that should be considered in all disorders is the functional status of the four stages of digestion. In the current paper, the relationship between stages of digestion and hyperlipidemia is clarified by referring to Traditional Iranian Medicine texts and the clinical evidence.