Background and Purpose: Literature Review and the aim of study Herbal treatment is obviously considered important in some prophetic and Islamic leaders. Literary heritage of Iran is influenced by Islamic cultures , traditions and beliefs . The study is aimed to reconcile herbal treatment of "cichorium Intybus" and "Rutaceae " according to Persian poets and research of contemporary medicine in Iran

Methods and Materials: Based on libraries procedure , the study has been done in three phases , Firstly , the application of herbal treatment of "cichorium Intybus" and " Reutaceae " has been studied in terms of valid poets and accounts in Shia.  Secondly , the similar applications of those herbals have been studied in Persian poets and literature. Thirdly, the applications have been studied in term of contemporary knowledge.  Some of the herbal treatments of "cichorium Intybus " are as followings ;Treatment dbylh , pleurisy , birth control , and mental illness. Herbal treatments of " Rutaceae" are as followings; Reduce inflammation and fever , moderation in bowel , and treatment of liver disorders.

Results: Modern medical research is confirmed the treatment application of both cichorium “Intybus” and “Rutaceae” Ordered in Persian literature and poets. The comparative application is insisted on speech of religious leaders and Islamic traditional beliefs which are clearly become visible in Persian literature and more over it can be shown the relationship between contemporary knowledge and ancient culture of Iran