Background and Purpose: Perineal painfollowingepisiotomyis oneof the common problemsin thefirst daysafter the birthmotherhasmany negativeconsequencesontheirfirst experienceofmotherhood. So the study purpose was toevaluate the effect of honey cream on intensity of pain of episiotomy was performed in nulliparous women.

Materials and methods: This research was conducted with double- blind randomized clinical  trial on 120 nulliparous womenIn three groups during 2013-2014 years inKashan.  . After delivery and episiotomy, mothers used a knuckle of prescribed honey cream, phenytoin cream or placeboin their sutures zone, every night for 10 nights. Tools contained demographic and midwifery information questionnaire, the form of numerical rating scale of pain and forms of drug effects and consumption of pain reliever. Evaluation of pain intensity with numerical rating scale of pain, took place in the first 24 hours and on the seventh and fourteenth days after delivery. In order to analyze the data, one-way ANOVA, Kruskal Wallis and Chi-square tests were used.

Results: Three groups according todemographic and midwifery information questionnaire were notsignificantly different. Measuring pain intensity was considered as the base line values in  24 hours after delivery and the pain intensity did not show any meaningful difference in the three groups in the seventh and fourteenth days after delivery (P=0.8 , P=0.19).

Conclusions: Use honey cream and phenytoin cream does not decreased intensity of pain of episiotomy. Therefore is recommended further research to evaluate the effectiveness of thehoney cream and phenytoin cream for pain relief.