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Showing 5 results for Akbarzadeh
S. Akbarzadeh, H. Mahjoub, N. Bazazi,
Volume 5, Issue 2 (summer 2014)
Abstract
Background and Purpose: Age related macular degeneration (AMD) is one of the most prevalent causes of blindness in people over 50 years of age. It occurs in dry and wet types. Dry type is more prevalent. The aim of this study is to evaluate the efficacy of herbal drug of HESA-A on dry AMD.
Material and Methods: Inclusion criteria were mild or moderate loss of vision due to AMD including: non-central geographic atrophy, RPE changes, multiple intermediate drusens (64-124 microns) or one large drusen ( diameter more than 124 microns) at least in one eye .Patients were randomized in drug and placebo groups ,so 29 of them received HESA- A and 30 patients received placebo. Patients were followed up at least one year. Patients were examined by an ophthalmologist every month and the results were recorded.
Results: Before intervention, mean of visual acuity were 0.15 log in right eye and 0.19 log in left eye in HESA-A group which changed to 0.14 log and 0.16 log respectively, at end of study. On the other side, before intervention, mean of visual acuity were 0.17 log in right eye and 0.16 log in left eye in placebo group which changed to 0.18 log and 0.18 log respectively. Difference of mean visual acuity changes in two groups was significant.( P<0.05)
Conclusions: Our study indicates that the use of herbal drug of HESA-A in moderate dry AMD, in comparison to placebo, induces mild visual acuity improvement and prevents further visual acuity loss; furthermore HESA-A does not have any ocular or systemic side effects.
R. Sabourian, E. Karimpour-Razkenari, T. Kazemi, T. Akbarzadeh, M. Saeedi, H. Rezaeizadeh, M. Khanavi, M. Shams Ardekani,
Volume 6, Issue 3 (fall 2015)
Abstract
Background and Purpose: Long-term complications of diabetes have encouraged scientists to develop comprehensive investigations for the prevention and control of diabetes. At this juncture, diet and lifestyle changes as well as physical activity are the main solutions. Iranian Traditional Medicine (ITM) with a thousand years of experience has paid special attention to health care principles which are known as “Sete Zarorie”. They have been frequently recommended to reduce or eliminate the risk of diabetes.
Material and Methods: In this review article, all the corresponding texts in traditional medicine and modern medicine were comprehensively studied. For this purpose, important Iranian traditional medicine references such as the Al Qanun-fil-Tibb, Tibb Akbari, Gharayez-al-Tabieh, Hefz-al-Sehe Naseri, Kholaseh-al-Hekmah, Mofaereh-al-Gholob, Alhavi-fil-Tibb as well as scientific data bases such as Iranmedex, Cochrane, CRD, Embase, Pub Med, SID, MEDLIN, Scopus, and Google Scholar using key words like “lifestyle”, “hyperglycemia”, “diabetes”, “fast blood sugar”, “prevention”, and “non-medicine” were carefully reviewed and the corresponding papers were studied. Two researchers reviewed the literature individually and the corresponding articles were studied and analyzed.
Results: It was found that the most solutions for the prevention and control of diabetes including suitable diet, weight loss, physical activity, and improving personal and sleep habits are same in both traditional and modern medicines. It should be noted that suitable solutions in ITM are recommended focusing on the “temperament”.
Conclusion: Considering the fact that recommended solutions for the prevention and control of diabetes in ITM are user-friendly, they deserve to be performed in the society under supervision of related specialists.
M. Bozorgi, Mr. Shams Ardekani, M. Khanavi, M. Saeidi, T. Akbarzadeh,
Volume 9, Issue 2 (Summer 2018)
Abstract
Background and Purpose: Cancer is one of the leading causes of mortality worldwide. In recent years, the rate of cancer has been dramatically rising. Side effects and, in some cases, inefficiencies in common treatments have led to extensive research about new drugs, especially those with plant origin. The study of traditional medical knowledge can lead to the selection of effective plants for cancer treatment. Pistacia atlantica is one of the herbs that had been considered by the ancient scientists for different diseases including cancer. This plant has been mentioned in traditional manuscripts with Arabic words like "Botm", "Elk-ol-Botm", and "Habat-ol-Khazra".
Methods and Materials: In this study, the main traditional manuscripts were searched with Pistacia atlantica related keywords in addition to different words that refer to malignancy like "Saratan" ,"Khanazir", "Saqhirus" and "Jozam". Moreover, scientific databases such as Iran medex, Cochrane, PubMed, SID, Medline, Scopus, and Google Scholar were searched using keywords such as: Pistacia atlantica, Saqez, and Bane.
Results: Based on the results of this study, several anticancer formulations containing the resin of Pistacia atlantica was found in traditional medicine manuscripts. In recent studies, various parts of the plant have been shown to be effective in controlling and inhibiting the proliferation of different types of cancer cells.
Conclusion: So far, various compounds have been identified in Pistacia atlantica, such as phenolic compounds which have antioxidant effects and induce apoptosis in cancer cells. Regarding many indications available in traditional and modern medicine about the anticancer effects of this plant, it can be concluded that Pistacia atlantica has a high potential for further investigations, especially in the form of clinical studies, in order to obtain new anti-cancer drugs.
Yasaman Vahedi-Mazdabadi, Mahbubeh Bozorgi, Fatemeh Farjadmand, Marya Binesh Marvasti, Tahmineh Akbarzadeh, Mahnaz Khanavi, Mina Saeedi,
Volume 9, Issue 4 (winter 2019)
Abstract
Background and purpose: Cardiovascular diseases (CVDs) are among the most common and prevalent diseases which are responsible for a majority of the morbidity, mortality, and health care costs worldwide. Hence, prevention and treatment of CVDs is essential for maintaining public health as well as economic benefits. In this respect, Persian medicine (PM) has recommended several practical comments based on the minerals for the prevention and treatment of heart diseases which will be discussed in this paper.
Methods and Materials: This article describes the role of minerals in the prevention and treatment of CVDs according to the comments recommended in PM. The study is based on the systematic search of PM sources such as Al Qanun-fi al-Tibb, Exir-e-Azam, Moalejat-e-Aghili, Makhzan-al-Advieh as well as Pub Med, Google Scholar, Scopus, SID, Iran medex, Magiran, Noor database using keywords: "Heart disease", "Heart tonic", "Heart disease", "Heart recreating", "Cardiovascular disease", "Risk factor", "Prevention", and "Mineral remedies". All results were extracted and analyzed comprehensively.
Results: Heart is a significant organ known as "chief organ" in PM. In this regard, there are a wide range of useful comments to improve or maintain heart health usually based on the herbal and mineral prescriptions as well as spiritual practice. In the case of minerals, ruby, gold, silver, turquoise and emerald have been found highly effective in the prevention and treatment of CVDs.
Conclusion: According to PM, using minerals such as gold, silver, pearl, amber, coral, lapis armenus, ambergris, ruby, azure, turquoise, opal, jade, garnet stone badakhshan, emerald, and iron, alone or in combination with other minerals, leads to the prevention and treatment of cardiovascular diseases. They may be used through different procedures including oral administration, wearing, keeping in mouth, and looking at them.
Majid Balaei Kahnamoei, Mahbubeh Bozorgi, Mahnaz Khanavi, Mohammad Reza Shams Ardekani, Tahmineh Akbarzadeh, Mina Saeedi, Mannan Hajimahmoodi,
Volume 10, Issue 1 (spring 2019)
Abstract
Background and Purpose: Henna belongs to the genus Lawsonia from the Lythraceae family. This shrub plant is about 2 meters high which is often planted in order to use its leaves, but other parts of the plant such as skin and seeds also have therapeutic effects. Henna grows in Iran, Pakistan, India, and South Asia as well as tropical and subtropical areas of East Africa. The distribution of henna in Iran includes Hormozgan, Khuzestan, Kerman and Sistan Baluchestan. The aim of this study was to investigate the therapeutic effects of henna in Persian medicine texts and to gathering data about the new evidences for the effects of henna.
Methods and Materials: It was a review study based on a library search in the main sources of Persian medicine in Iran. Also, various databases such as Google Scholar, PubMed, and Science Direct were searched for new findings.
Results: Henna (Lawsonia innermis L.) is widely used in Persian medicine to treat many diseases including skin and hair disorders, headaches, and wound healing. Henna leaves powder is used in dyeing of hair, beard, and nails. Henna, in terms of phytochemistry, includes compounds such as quinones, carbohydrates, proteins, flavonoids, tannins and phenolic compounds, alkaloids, coumarins, and fatty acids. The most important features of henna plant are analgesic, hypoglycemic, hepatoprotective, anti-inflammatory, antimicrobial, antimicrobial, antifungal, antiviral, immune stimulant, antioxidant, and anti-cancer properties.
Conclusion: Comparing and adapting traditional findings and current studies suggests that there is a very close match between Persian medicine and conventional medicine sources. Hence, considering new practical findings of the henna and a closer look at the sources of Persian medicine especially ancient manuscripts may lead to discover novel effective pharmaceutical products.
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