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Effect of Pistacia atlantica on cancer treatment: a review of traditional manuscripts and recent publications
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| M. Bozirgi , M.R Shamse ardakani , M. Khanavi , M. Saeidi , T Akbarzade * |
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Abstract: (2130 Views) |
Background: Cancer is one of the leading causes of mortality in the world, and in recent years, the rate of cancer has been dramatically rising. Side effects and, in some cases, inefficiencies in common treatments have led to extensive research into new drugs, especially from plant sources. The study of traditional medicine knowledge can lead to the selection of effective plants for cancer treatment. Pistacia atlatica is one of the herbs that be considered by ancient scientist for different diseases including cancer. This plant has been mentioned in traditional manuscripts with Arabic words like “botm,بُطم ” ; “ Elk-ol-botm, علکالبطم”and “ habat-ol-khazra,حبهالخضراء”.
Methods: In this study the main traditional manuscripts were searched with Pistacia atlatica related key-words in addition to different words that refer to malignancy like “ Saratan,سرطان”, “Khanazir, خنازیر”, “Saqhirus,سقیروس”and “Jozam, جذام”. Moreover, scientific data bases such as Iranmedex, Cochrane, CRD, Embase, Pub Med, SID, MEDLIN, Scopus, and Google Scholar using key words like Pistacia atlantica, Saqez and Bane.
Results: Based on the results of this study, several anticancer formulations containing the resin of P. atlatica havebeen found that in traditional medicine manuscripts. In recent studies, various parts of the plant have been shown to be effective in controlling and inhibiting the proliferation of different types of cancer cells.
Discussion and Conclusion:
So far, various compounds have been identified in P. atlantica, such as phenolic compounds, that have antioxidant effects and induced apoptosis in cancer cells. Regarding the many indications available in traditional and modern medicine about the anticancer effects of this plant, it can be conclded that P. atlantica has a high potential for further investigation, especially in the form of clinical studies, in order to obtain new anti-cancer drugs |
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| Keywords: Phstacia atlantica, traditional medicine, cancer |
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Type of Study: Research |
Subject:
Special
Received: 2018/10/15 | Accepted: 2018/10/15 | Published: 2018/10/15
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