It seems that in spite of huge investments made in history of Iranian medicine in recent years, the investments and the perspective of results obtained in studies of history of the Islamic era medicine is not what was expected. A reason for this phenomenon can be absence of perspective and theoretical studies in this field. In this study, after explaining the how’s and why’s of the theory development in history of medicine, we address the infrastructures required for theory development atmosphere. By introducing some of these infrastructures, we would evaluate some concerns about the essence of theory development in history of Islamic medicine.