Cholera was the main deadly and widespread disease which killed many Iranians in Qajar Era. The main question of this research is the ways of prevention and curing of the disease in the Era and finding the main reasons of people's fortunate to have the common treatments to cure the disease.

The main hypothesis of this research is about the effects of lacking of modern knowledge in Iran, people had to use of common treatments for deadly and widespread diseases. One of the most important of the treatments was prayers and Talismans. Unfortunately, up to now, there is not any seriouse research about common traditional ways of Treatements of diseases in diferent historical eras. Then, we can consider this article as a first step to lead following researchers to study about the common ideas of social history of the Iranians.