The existence and quality of medical system among various civilizations has demonstrated the importance of that tribes and medical capabilities of them. One of these systems was Shiraz Medical School which historians and scholars have been less attention to it. Scientific school of Shiraz was label as a Dar-ol Elm and by having scientific schools, hospitals and medical centers and equipped libraries gained international reputation. The great scholars and scientists began to foot in this field that have developed new ways and cause medical progress and prosperity. On previous number of this publication we review the medical school from Al-bouyeh period to beginning of Safavid dynasty, in this research continue to review and analysis the medical school from Safavid dynasty to the end of Qajar.